PureOptic

isa viscous ophthalmic liquid that may be administered as eye drops or via sub palpebral lavage (SPL). In other regenerative eye products, the active ingredient consists primarily of micronized membrane.While membrane alonecanhave positive effects, research has shown that it does not provide the same level of cell-signaling as our proprietary formulation of exosomes, growth factors, and other proteins to stimulate the healing process.

The Hilltop Bio Difference

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Optimized Viscosity Ensures Solution Stays in Place Longer
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Customized Active Component Levels to Boost Healing
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Room-temperature & Ready to Use in Under a Minute
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Strict cGMP/cGTP Manufacturing Standards

Cases

Immune Mediated Keratitis

Corneal Ulcer

PureOptic administered via SPL

View our Case Studies page for additional examples.

References:

  1. Costa, Daniel et al. “A multicenter retrospective study on cryopreserved amniotic membrane transplantation for the treatment of complicated corneal ulcers in the dog.” eVeterinary ophthalmology vol. 22,5 (2019): 695-702.
  2. Henriksen, M de Linde et al. “Visual outcome after corneal transplantation for corneal perforation and iris prolapse in 37 horses: 1998-2010.” Equine veterinary journal. Supplement ,43 (2012): 115-9.
  3. Kubo M, Sonoda Y, Muramatsu R, et al. Immunogenicity of human amniotic membrane in experimental xenotransplantation. Invest Ophthalmol Visual Sci 2001;42:1539-1546.
  4. Lassaline, Mary E et al. “Equine amniotic membrane transplantation for corneal ulceration and keratomalacia in three horses.” Veterinary ophthalmology vol. 8,5 (2005): 311-7.
  5. Plummer, C. The use of amniotic membrane transplantation for ocular surface reconstruction: a review and series of 58 equine clinical cases (2002-2008). Vet Ophthal, 2009(12), Supplement, 17-24.