Hilltop Bio is a veterinary biotechnology company focused on the research and development of biologically derived products. Our products are designed for convenience, room-temperature stability, and ease of use—offering veterinary professionals off-the-shelf options to support their clinical workflows.

Yes. Hilltop Bio products are manufactured under stringent quality control measures, following current Good Manufacturing Practices (cGMP)-inspired protocols to promote consistency and reliability. While cGMP may not be legally required for all veterinary products, we voluntarily implement these standards as part of our commitment to high-quality manufacturing. As with any veterinary product, use should be guided by a licensed veterinarian, as individual animal responses may vary.

Most Hilltop Bio products are intended for use by licensed veterinarians or veterinary professionals operating under their supervision. However, we do offer a topical product that is available for purchase directly through our website without requiring a veterinary license.

Hilltop Bio products are shelf-stable and do not require refrigeration prior to use. However, once a product is reconstituted, specific storage guidelines apply. Reconstituted products typically need to be refrigerated and used within a defined timeframe. For example, Regenaflex-Gel and PureOptic should be refrigerated between uses once reconstituted. Each shipment includes detailed handling and storage instructions to ensure proper use.

Veterinary products are regulated differently from human drugs, and not all require FDA approval. Hilltop Bio is committed to regulatory transparency and is actively engaging with the FDA’s Center for Veterinary Medicine (CVM) to help ensure our practices align with applicable guidelines and expectations.

Yes, we do offer international shipping. If you are a first-time international client, we recommend contacting us prior to placing an order, as some countries may have import restrictions on biologically derived products. Please reach out to us at info@hilltopbio.com to confirm product availability and shipping options in your region.

Yes. We provide educational resources and support for veterinary professionals. For assistance, email us at info@hilltopbio.com.

Veterinary biologics are products derived from natural biological sources—such as cells, tissues, or proteins—that interact with the body’s biological systems. These products are often used in veterinary practice to support physiological functions. The term typically refers to vaccines, diagnostic tools, and other biologically based materials regulated by agencies such as the USDA or FDA, depending on their intended use and classification.

Hilltop Bio products are intended to complement veterinary care in cases where biologically derived materials may be appropriate. They are commonly used by veterinary professionals as part of strategies related to tissue management, recovery support, and overall case management. Use should always be determined by a licensed veterinarian based on clinical judgment and individual patient needs.

Administration methods vary by product and case and may include intramuscular (IM), intra-articular, subcutaneous, or topical application. All products are intended for use by, or under the supervision of, a licensed veterinarian. Detailed handling and administration guidelines are provided with each product.

The number of applications varies based on the specific product, case complexity, and clinical judgment. In some situations, a single application may be sufficient, while other cases may require multiple uses. Veterinary professionals determine the appropriate approach based on individual patient needs.

As with many injectable products, temporary inflammation or irritation at the application site may occur. These responses are typically mild and may resolve within a few days. In some cases, light activity or continued movement may help support normal recovery. All use should be monitored by a licensed veterinarian, who can determine the appropriate response if any side effects arise.

Response times can vary depending on the product used, the individual animal, and the specific clinical situation. Your veterinarian will assess progress over time and determine if additional applications are appropriate based on their professional judgment.

Yes. Hilltop Bio products are often incorporated into broader care plans by veterinary professionals. They may be used in conjunction with modalities such as shockwave, ultrasound, laser therapy, hydrotherapy, and rehabilitation exercises. All use—including concurrent applications—should be directed by a licensed veterinarian based on clinical judgment and individual patient needs.

Nonsteroidal anti-inflammatory drugs (NSAIDs) may be used concurrently at the discretion of your veterinarian. While Hilltop Bio has conducted internal research on product compatibility, all decisions regarding concurrent use should be based on the clinical judgment of the attending veterinary professional..

Yes. Each Hilltop Bio product includes detailed usage and administration instructions intended for licensed veterinary professionals. These guidelines are designed to support appropriate application based on the product and clinical context.

Hilltop Bio products contain biologically derived materials such as extracellular matrix proteins, cytokines, exosomes, tissue inhibitors of metalloproteinases (TIMPs), collagen, hyaluronic acid, and microRNA. These materials are naturally present in tissue and do not include any synthetic additives. To learn more, please read Active Components

The biologically derived materials in Hilltop Bio products are known to play roles in cell signaling and communication. In natural settings, molecules such as cytokines, exosomes, and extracellular matrix proteins are involved in intercellular signaling that may influence various cellular behaviors. Ongoing research continues to explore how these components interact with the biological environment in veterinary applications.

Hilltop Bio sources tissues in collaboration with experienced reproductive veterinarians across the United States. Tissues are collected non-invasively during the natural birth of healthy foals from healthy mares. No tissue is collected via cesarean section, and the collection process is designed to ensure the well-being of both mare and foal.

Yes. All donor mares undergo a thorough screening process prior to tissue collection. This includes a review of medical and travel history to ensure eligibility. If the initial criteria are met, blood samples are submitted to a certified third-party laboratory for testing. These tests screen for a range of infectious agents, including equine infectious anemia (EIA), Brucella, parvovirus, tick-borne illnesses, and others, in accordance with our quality and safety protocols.

Exosomes and growth factors are naturally occurring components involved in intercellular communication. In biological systems, they help coordinate cell-to-cell signaling and may influence local processes such as tissue maintenance, cellular signaling, and regulation of the biological environment. Ongoing research continues to explore their roles in veterinary applications.

Hilltop Bio’s development process includes ongoing research, internal data collection, and collaboration with veterinary professionals. While some findings have been shared through scientific and clinical channels, not all data is currently published in peer-reviewed journals. We are committed to scientific transparency and welcome inquiries from veterinarians seeking product-specific information or references.

Email: info@hilltopbio.com
Phone: (617) 237-0636